Inhibition of the behavioral effects of mirtazapine by WAY100635 on beam-walking test and rota-rod test. (A) Beam-walking test: Vertical axis shows the periods required to traverse 50 cm of the beam. (B) Rota-rod test: Vertical axis shows the latency to fall from the rotating rod after the mice were placed on it. Values are expressed as means ± SEM, n = 9–10 mice/group. Statistical significance was evaluated by one-way ANOVA followed by (A) Scheffe test and (B) Student-Newman-Keuls test. (F(A) 3,35 = 18.962, F(B) 3,35 = 5.488, *P < 0.05, **P < 0.01 compared with MPTP-treated group and †P < 0.05 compared with MPTP + mirtazapine group).