Figure 5From: The expression of apoptosis inducing factor (AIF) is associated with aging-related cell death in the cortex but not in the hippocampus in the TgCRND8 mouse model of Alzheimer’s diseaseAIF expression in cortical (A), hippocampal (B) and cerebellar (C) extracts from Tg mice and their age-matched non-Tg littermates at indicated ages. Both mitochondrial (62 kDa, white bars) and tAIF (57 kDa, black bars) forms of AIF were studied. Equal protein loading was confirmed by detection of β-actin. Results were expressed as the ratio of the values calculated for the transgenic over non-Tg mice. *P < 0.05; #P < 0.01; ##P < 0.001; ###P < 0.0001.Back to article page