Figure 1From: Tics are caused by alterations in prefrontal areas, thalamus and putamen, while changes in the cingulate gyrus reflect secondary compensatory mechanismsGroup comparison of TS and normal controls. FA results are superimposed on the mean of all subjects of spatially normalized anisotropy images. Voxels with a significant decrease in FA in TS patients versus controls were found in the white matter of the medial prefrontal cortex below BA 10, the left inferior frontal gyrus (below BA 44), and the cingulate gyrus (p < 0.001, uncorrected).Back to article page