Table 2 Effect of MAPT rs242562 and GSK3B rs334558 on risk for PD
From: MAPT rs242562 and GSK3B rs334558 are associated with Parkinson’s Disease in central China
SNPs | OR (95% CI) | P | Crude OR (95% CI) | P | Adjusted OR (95% CI)* | P | Crude OR (95% CI) | P | Adjusted OR (95% CI)* | P |
|---|---|---|---|---|---|---|---|---|---|---|
rs242562 (A/G) | Allele-wise A vs. G | AA vs. AG + GG | AA vs. AG + GG | AG + AA vs. GG | AG + AA vs. GG | |||||
1.278 (0.980-1.666) | 0.071 | 1.087 (0.711 – 1.662) | 0.7 | 1.065 (0.693 – 1.636) | 0.775 | 1.853 (1.169 – 2.936) | 0.009 | 1.785 (1.116 – 2.853) | 0.016 | |
Power | 0.266 | 0.058 | 0.048 | 0.793 | 0.745 | |||||
rs334558 (T/C) | Allele-wise T vs. C | TT vs. CT + CC | TT vs. CT + CC | CT + TT vs.CC | CT + TT vs. CC | |||||
1.060 (0.814-1.381) | 0.667 | 1.080 (0.612 – 1.907) | 0.79 | 1.018 (0.573 – 1.808) | 0.951 | 1.088 (0.746 – 1.588) | 0.661 | 1.058 (0.719 – 1.557) | 0.774 | |
Power | 0.05 | 0.044 | 0.029 | 0.064 | 0.064 |