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Table 1 Allele and Genotype frequencies of MAPT rs242562 and GSK3B rs334558 in PD cases and controls

From: MAPT rs242562 and GSK3B rs334558 are associated with Parkinson’s Disease in central China

  Case(211) Control(279)
  Number % Number % Number % Number % Number % Number %
rs242562
Allele A   G     A   G    
Total 230 55.02 188 44.98    225 48.91 235 51.09   
Male 149 54.78 123 45.22    140 48.61 148 51.39   
Female 81 55.48 65 44.52    85 49.42 87 50.58   
Age < =50 80 54.05 68 45.95    102 43.97 130 56.03   
Age > 50 150 55.56 120 44.44    123 53.95 105 46.05   
Genotype AA   AG   GG   AA   AG   GG  
Total 57 27.27 116 55.5 36 17.22 59 25.65 107 46.52 64 27.83
Male 37 27.21 75 55.15 24 17.65 36 25 68 47.22 40 27.78
Female 20 27.4 41 56.16 12 16.44 23 26.74 39 45.35 24 27.91
Age < =50 20 27.23 40 54.05 14 18.92 27 23.28 48 41.38 41 35.34
Age > 50 37 27.41 76 56.3 22 16.3 32 28.07 59 51.75 23 20.18
rs334558
Allele C   T     C   T    
Total 260 61.61 162 38.39    330 62.98 194 37.02   
Male 170 62.04 104 37.96    218 63.74 124 36.26   
Female 90 60.81 58 39.19    112 61.54 70 38.46   
Age < =50 97 65.54 51 34.46    163 65.73 85 34.27   
Age > 50 163 59.49 111 40.51    167 60.51 109 39.49   
Genotype CC   CT   TT   CC   CT   TT  
Total 74 35.07 112 53.08 25 11.85 97 37.02 136 51.91 29 11.07
Male 53 38.69 64 46.72 20 14.6 62 36.26 94 54.97 15 8.77
Female 21 28.38 48 64.86 5 6.76 35 38.46 42 46.15 14 15.38
Age < =50 27 36.49 43 58.11 4 5.41 52 41.94 59 47.58 13 10.48
Age > 50 47 34.31 69 50.36 21 15.33 45 32.61 77 55.8 16 11.59
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