From: MAPT rs242562 and GSK3B rs334558 are associated with Parkinson’s Disease in central China
Case(211) | Control(279) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Number | % | Number | % | Number | % | Number | % | Number | % | Number | % | |
rs242562 | ||||||||||||
Allele | A | G | A | G | ||||||||
Total | 230 | 55.02 | 188 | 44.98 | 225 | 48.91 | 235 | 51.09 | ||||
Male | 149 | 54.78 | 123 | 45.22 | 140 | 48.61 | 148 | 51.39 | ||||
Female | 81 | 55.48 | 65 | 44.52 | 85 | 49.42 | 87 | 50.58 | ||||
Age < =50 | 80 | 54.05 | 68 | 45.95 | 102 | 43.97 | 130 | 56.03 | ||||
Age > 50 | 150 | 55.56 | 120 | 44.44 | 123 | 53.95 | 105 | 46.05 | ||||
Genotype | AA | AG | GG | AA | AG | GG | ||||||
Total | 57 | 27.27 | 116 | 55.5 | 36 | 17.22 | 59 | 25.65 | 107 | 46.52 | 64 | 27.83 |
Male | 37 | 27.21 | 75 | 55.15 | 24 | 17.65 | 36 | 25 | 68 | 47.22 | 40 | 27.78 |
Female | 20 | 27.4 | 41 | 56.16 | 12 | 16.44 | 23 | 26.74 | 39 | 45.35 | 24 | 27.91 |
Age < =50 | 20 | 27.23 | 40 | 54.05 | 14 | 18.92 | 27 | 23.28 | 48 | 41.38 | 41 | 35.34 |
Age > 50 | 37 | 27.41 | 76 | 56.3 | 22 | 16.3 | 32 | 28.07 | 59 | 51.75 | 23 | 20.18 |
rs334558 | ||||||||||||
Allele | C | T | C | T | ||||||||
Total | 260 | 61.61 | 162 | 38.39 | 330 | 62.98 | 194 | 37.02 | ||||
Male | 170 | 62.04 | 104 | 37.96 | 218 | 63.74 | 124 | 36.26 | ||||
Female | 90 | 60.81 | 58 | 39.19 | 112 | 61.54 | 70 | 38.46 | ||||
Age < =50 | 97 | 65.54 | 51 | 34.46 | 163 | 65.73 | 85 | 34.27 | ||||
Age > 50 | 163 | 59.49 | 111 | 40.51 | 167 | 60.51 | 109 | 39.49 | ||||
Genotype | CC | CT | TT | CC | CT | TT | ||||||
Total | 74 | 35.07 | 112 | 53.08 | 25 | 11.85 | 97 | 37.02 | 136 | 51.91 | 29 | 11.07 |
Male | 53 | 38.69 | 64 | 46.72 | 20 | 14.6 | 62 | 36.26 | 94 | 54.97 | 15 | 8.77 |
Female | 21 | 28.38 | 48 | 64.86 | 5 | 6.76 | 35 | 38.46 | 42 | 46.15 | 14 | 15.38 |
Age < =50 | 27 | 36.49 | 43 | 58.11 | 4 | 5.41 | 52 | 41.94 | 59 | 47.58 | 13 | 10.48 |
Age > 50 | 47 | 34.31 | 69 | 50.36 | 21 | 15.33 | 45 | 32.61 | 77 | 55.8 | 16 | 11.59 |