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Figure 2 | BMC Neuroscience

Figure 2

From: Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?

Figure 2

Nitrate/Nitrite content profiling of CSE from tested tobacco products. (A) Nitrate/nitrite content increased proportionally to the amount of tar in the cigarettes where statistically significant higher nitrate was found in ultralow nicotine than ultralight cigarette (P < 0.001, n = 10 biological replicates). Nicotine free cigarettes which were non-tobacco based did not have significant nitrate/nitrite content. Regression analysis of Nitrate/Nitrite correlates with tar (B) but not nicotine content unless ultralow nicotine cigarettes are removed from the analytical pool (C).

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