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Table 2 Average morphometric data of the renal nerves fascicles from the six experimental groups: acute diabetic group (15 days after STZ injection), acute treated group, acute control group, chronic diabetic group (12 weeks after STZ injection), chronic treated group and chronic control group

From: Renal nerve ultrastructural alterations in short term and long term experimental diabetes

 

Acute diabetic

Acute treated

Acute control

Chronic diabetic

Chronic treated

Chronic control

Fascicular area (μm2)

5030 ± 1200

4470 ± 619

3585 ± 672

7834 ± 1103*

6212 ± 547

5300 ± 1177

Fascicular diameter (μm)

76 ± 9

74 ± 5

64 ± 7

124 ± 19*

88 ± 4

83 ± 12

Myelinated fiber number

6 ± 2

9 ± 2

6 ± 1°

10 ± 3

13 ± 2

19 ± 7

Myelinated fiber density (number of fiber/μm2)

1470 ± 411

2113 ± 441

1949 ± 759

1333 ± 295°

2105 ± 292

3885 ± 1124

Schwann cell nucleus number

34 ± 4

24 ± 4

32 ± 6

44 ± 8

42 ± 3+

38 ± 7

Schwann cell nucleus density (number of nucleus/μm2)

9043 ± 1420

6013 ± 950

10650 ± 1752

5517 ± 544*

6897 ± 662

8424 ± 1606

Unmyelinated fiber number

1821 ± 330

2289 ± 342

1322 ± 230

1481 ± 175

1573 ± 218

1237 ± 98

Unmyelinated fiber density (number of fiber/μm2)

408219 ± 41358+

578601 ± 96603

379066 ± 38120+°

211857 ± 31431°

256855 ± 33371+°

288967 ± 31934

  1. *Indicates difference compared to acute diabetic group, +indicates difference compared to acute treated, °indicates difference compared to chronic control.