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Table 2 Average morphometric data of the renal nerves fascicles from the six experimental groups: acute diabetic group (15 days after STZ injection), acute treated group, acute control group, chronic diabetic group (12 weeks after STZ injection), chronic treated group and chronic control group

From: Renal nerve ultrastructural alterations in short term and long term experimental diabetes

  Acute diabetic Acute treated Acute control Chronic diabetic Chronic treated Chronic control
Fascicular area (μm2) 5030 ± 1200 4470 ± 619 3585 ± 672 7834 ± 1103* 6212 ± 547 5300 ± 1177
Fascicular diameter (μm) 76 ± 9 74 ± 5 64 ± 7 124 ± 19* 88 ± 4 83 ± 12
Myelinated fiber number 6 ± 2 9 ± 2 6 ± 1° 10 ± 3 13 ± 2 19 ± 7
Myelinated fiber density (number of fiber/μm2) 1470 ± 411 2113 ± 441 1949 ± 759 1333 ± 295° 2105 ± 292 3885 ± 1124
Schwann cell nucleus number 34 ± 4 24 ± 4 32 ± 6 44 ± 8 42 ± 3+ 38 ± 7
Schwann cell nucleus density (number of nucleus/μm2) 9043 ± 1420 6013 ± 950 10650 ± 1752 5517 ± 544* 6897 ± 662 8424 ± 1606
Unmyelinated fiber number 1821 ± 330 2289 ± 342 1322 ± 230 1481 ± 175 1573 ± 218 1237 ± 98
Unmyelinated fiber density (number of fiber/μm2) 408219 ± 41358+ 578601 ± 96603 379066 ± 38120+° 211857 ± 31431° 256855 ± 33371+° 288967 ± 31934
  1. *Indicates difference compared to acute diabetic group, +indicates difference compared to acute treated, °indicates difference compared to chronic control.