Figure 3

Efficacy of antidotes on soman induced neurodegeneration. Efficacy of antidotes (HI-6 (50 mg/kg, i.m), atropine (10 mg/kg, i.m) and midazolam (5 mg/kg, i.m) on soman induced neurodegeneration: Representative photomicrographs of Fluoro-Jade B stained cerebral cortex, hippocampus (CA1 sub region) and cerebellum regions obtained from vehicle (A, B and C) and after antidotes + soman treatment animals sacrificed at 2 h (D, E and F), 1 day (G, H and I), 7 day (J, K and L) time points (n = 4 per each time point) taken with 100 magnifications.