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Table 3 Summary of the variations from PFC metabolites in mice

From: 1H-Nuclear magnetic resonance-based metabolomic analysis of brain in mice with nicotine treatment

Metabolites

Chemical shift

Control-nicotine

 

(ppm)

VIPa

Loadingb

Cystine

3.36

5.83

-0.354

Arginine

3.76

2.90

+0.217

Glucose

3.40

2.52

-0.074

Glutamate

2.04

2.06

+0.156

3-Hydroxybutyric acid

1.20

2.05

-0.151

Uracil

7.52

2.03

-0.151

NAD

8.84

1.99

-0.150

Acetone

2.24

1.92

+0.145

Phosphocholine

4.16

1.83

+0.135

L-Phenvlalanine

3.12

1.80

-0.133

  1. aVariable importance in the projection (VIP ≥ 1) was obtained from OSC-PLS.
  2. bLoading: the positive (+) value represents an increase of the metabolite in the second group of the subtitle (e.g.: Control → Nicotine), while the negative (-) value represents a decrease of the metabolite in the second group of the subtitle.
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BMC Neuroscience

ISSN: 1471-2202

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