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Table 1 Summary of the variations from hippocampus metabolites in mice

From: 1H-Nuclear magnetic resonance-based metabolomic analysis of brain in mice with nicotine treatment

Metabolites

Chemical shift

Control-nicotine

 

(ppm)

VIPa

Loadingb

Glutamate

2.08

6.07

-0.433

Cystine

3.36

4.64

-0.287

Creatine

3.04

3.88

-0.229

Glutathione

3.8

3.37

-0.258

1-Methylhistamine

3.68

3.28

-0.241

Taurine

3.28

2.79

-0.2 18

2-Ketobutyric acid

2.76

2.71

-0.167

*

3.6

2.19

-0.159

Glucose

3.40

2.11

-0.021

Lysine

1.36

2.09

-0.163

  1. aVariable importance in the projection (VIP ≥ 1) was obtained from OSC-PLS.
  2. bLoading: the negative (-) value represents a decrease of the metabolite in the second group of the subtitle (e.g.: Control → Nicotine).
  3. The symbol (*) represents a material which has not been identified.