Figure 3
From: Impact of methodology on estrogens’ effects on cerebral ischemia in rats: an updated meta-analysis
By three simple linear regression analyses, it was found that higher pellet doses significantly increased EC-ratio (y = 72.8 + 0.05x; p = 0.001), while there was an opposite trend (not significant) among injection and silastic capsule regimens. The numbers of group pairs included in the slow-release pellet, injection and silastic capsule simple regression models were 39, 50 and 31, respectively. Note that the injection graph has been compressed in the upper dose range to accommodate three group pairs being administered very high doses.