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Table 3 Receiver operating characteristics

From: Repeated mapping of cortical language sites by preoperative navigated transcranial magnetic stimulation compared to repeated intraoperative DCS mapping in awake craniotomy

Definition of rTMS-positive Error rate
≥5% ≥10% ≥15% ≥20% ≥25%
PPV 21% 24% 29% 21% 17%
NPV 93% 91% 89% 83% 82%
Sensitivity 90% 80% 60% 30% 10%
Specificity 28% 46% 67% 76% 89%
  1. ROC on the correlation of repetitive navigated transcranial magnetic stimulation (rTMS) to direct cortical stimulation (DCS) for the combined group of no responses and performance errors across all mappings of this report. PPV = positive predictive value, NPV = negative predictive value. DCS represents the ground truth. In the second row information is giving at which percentage of error rate a CPS region is defined as rTMS positive. According to this threshold level, we observe different patterns of correlation with intraoperative DCS.