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Figure 8 | BMC Neuroscience

Figure 8

From: Glutamic acid decarboxylase 1 alternative splicing isoforms: characterization, expression and quantification in the mouse brain

Figure 8

Expression of GAD1 Isoforms 7/8 and Isoforms 9/10 in adult mouse brain detected by in situ hybridization. Expression of Isoforms 7/8 (A-G) and expression of Isoforms 9/10 (H-J). Moderate expression of Isoforms 7/8 was detected in olfactory bulb (A). Low expression was detectable in olfactory tubercle and accumbens nucleus (B); cerebellum (C); lateral septal nucleus, ventral pallidum and striatum (D); suprachiasmatic nucleus (E); VMH and arcuate nucleus (F); hippocampus (G). Expression of Isoforms 9/10 could be detected only in olfactory bulb (H), hippocampus (I) and cerebellum (J). Acb, accumbens nucleus; aca, anterior commissure; AOB, accessory olfactory bulb; Arc, arcuate nucleus; Cpu, caudate putamen (striatum); cc, corpus callosum; DG, dentate gyrus; EPl, external plexiform layer of olfactory bulb; FrA, frontal association cortex; Gl, glomerular layer of olfactory bulb; GrO, granular cell layer of olfactory bulb; Gr, granular cell layer of cerebellum; LS, lateral septal nucleus; Mi, mitral cell layer of olfactory bulb; Mo, molecular cell layer of the cerebellum; P, Purkinje cells; Rt, reticular nucleus; Sch, suprachiasmatic nucleus; Tu, olfactory tubercle; VMH, ventromedial hypothalamic nucleus; VP, ventral pallidum. Scale bar = 100 μm (J), 200 μm (B, C, E, F and I), 300 μm (A, G and H). Scale bar = 1 mm (D).

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