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Table 2 Mean values of [1- 14 C] docosahexaenoic acid incorporation coefficient k*in acute saline- and quinpirole-treated rats

From: D2-like receptor activation does not initiate a brain docosahexaenoic acid signal in unanesthetized rats

Brain region Saline (n = 6) Quinpirole (n = 7)
Telencephalon   
Prefrontal cortex layer I 3.42 ± 0.87 3.00 ± 0.73
Prefrontal cortex layer IV 3.76 ± 0.98 3.66 ± 1.21
Primary olfactory cortex 3.28 ± 0.85 3.77 ± 1.76
Frontal cortex (10)   
Layer I 3.13 ± 0.79 3.88 ± 1.54
Layer IV 3.51 ± 1.00 4.26 ± 1.67
Frontal cortex (8)   
Layer I 3.38 ± 0.91 3.76 ± 1.77
Layer IV 3.66 ± 1.02 4.13 ± 1.91
Pyriform cortex 3.29 ± 0.60 3.12 ± 0.92
Anterior cingulate cortex 4.18 ± 0.93 5.06 ± 2.80
Motor cortex   
Layer I 3.35 ± 0.71 3.60 ± 1.39
Layer II – III 3.72 ± 0.88 4.39 ± 1.74
Layer IV 4.00 ± 0.92 4.42 ± 1.59
Layer V 3.35 ± 0.79 3.64 ± 1.35
Layer VI 3.25 ± 0.61 3.50 ± 1.29
Somatosensory cortex   
Layer I 3.61 ± 0.83 4.01 ± 1.57
Layer II–III 3.97 ± 0.88 4.68 ± 1.92
Layer IV 4.20 ± 1.03 4.57 ± 1.73
Layer V 4.09 ± 0.90 4.51 ± 1.72
Layer VI 3.93 ± 0.89 4.44 ± 1.72
Auditory cortex   
Layer I 4.09 ± 1.36 4.51 ± 1.29
Layer IV 4.07 ± 1.23 4.11 ± 1.22
Layer VI 3.62 ± 1.21 3.82 ± 1.18
Visual cortex   
Layer I 3.44 ± 1.10 4.17 ± 1.37
Layer IV 3.92 ± 1.24 4.52 ± 1.35
Layer VI 3.77 ± 1.14 4.38 ± 1.30
Preoptic area (LPO/MPO) 3.39 ± 0.76 3.48 ± 1.12
Suprachiasmatic nu 3.55 ± 0.90 3.73 ± 1.18
Globus pallidus 3.28 ± 0.71 3.83 ± 1.38
Bed nu striaterminalis 3.44 ± 0.76 3.58 ± 1.15
Olfactory tubercle 4.41 ± 1.06 4.39 ± 1.34
Diagonal band   
Dorsal 4.36 ± 1.07 3.92 ± 1.31
Ventral 4.11 ± 1.05 3.80 ± 1.36
Amygdala basolat/med 3.95 ± 0.86 3.65 ± 0.96
Hippocampus   
CA1 3.91 ± 0.85 3.36 ± 0.77
CA2 4.00 ± 0.91 3.41 ± 0.80
CA3 4.11 ± 0.92 3.69 ± 0.86
Dentate gyrus 4.29 ± 0.99 4.18 ± 1.05
SLM 4.49 ± 1.01 4.91 ± 1.92
Accumbens nucleus 3.45 ± 0.83 3.33 ± 1.16
Caudate putamen   
Dorsal 4.33 ± 1.00 3.67 ± 1.40
Ventral 4.35 ± 1.09 3.80 ± 1.29
Lateral 4.39 ± 1.00 3.76 ± 1.34
Medial 4.36 ± 1.04 3.68 ± 1.32
Septal nucleus lateral 3.90 ± 0.88 3.31 ± 1.20
medial 4.19 ± 1.01 3.84 ± 1.15
Diencephalon   
Habenular nu lateral 5.50 ± 1.15 5.75 ± 1.85
Habenular nu medial 5.48 ± 1.67 5.12 ± 1.60
Lateral geniculate nu dorsal 4.61 ± 1.91 4.19 ± 1.16
Medial geniculate nu 4.59 ± 1.81 4.83 ± 1.61
Thalamus   
Ventroposterior lateral nu 4.78 ± 2.14 4.08 ± 0.96
Ventroposterior medial nu 4.99 ± 2.15 4.31 ± 1.06
Paratenial nu 4.61 ± 0.88 4.46 ± 1.76
Anteroventral nu 5.91 ± 1.26 5.84 ± 2.41
Anteromedial nu 4.95 ± 1.11 4.61 ± 1.77
Reticular nu 4.98 ± 1.09 4.93 ± 2.08
Paraventricular nu 4.41 ± 0.87 4.23 ± 1.68
Parafascicular nu 4.88 ± 1.31 4.85 ± 1.70
Subthalamic nucleus 4.77 ± 1.47 4.93 ± 1.71
Hypothalamus   
Supraoptic nu 5.09 ± 1.47 5.34 ± 1.41
Lateral 3.89 ± 0.93 3.75 ± 1.29
Anterior 3.91 ± 1.00 3.90 ± 1.25
Periventricular 3.40 ± 1.00 3.29 ± 1.05
Arcuate 4.32 ± 1.20 4.66 ± 1.79
Ventromedial 4.03 ± 1.13 4.54 ± 1.87
Posterior 4.52 ± 0.92 4.01 ± 1.43
Mammillary nucleus 3.99 ± 1.62 4.59 ± 1.48
Zone Incerta 4.36 ± 1.40 4.18 ± 1.27
Mesencephalon   
Interpeduncular nucleus 5.09 ± 1.42 5.89 ± 2.18
Substantianigra 3.50 ± 0.99 4.45 ± 1.75
Pretectal area 4.07 ± 1.18 4.92 ± 1.92
Superior colliculus 4.17 ± 1.07 5.38 ± 2.28
Deep layers 4.05 ± 1.25 4.71 ± 1.12
Inferior colliculus 6.62 ± 2.06 7.01 ± 2.52
Rhombencephalon   
Flocculus 5.67 ± 1.68 6.16 ± 2.24
Cerebellar gray matter 5.58 ± 1.65 6.59 ± 2.31
Molecular layer cerebellar   
gray matter 6.54 ± 1.45 7.23 ± 2.96
White matter   
Corpus callosum 2.74 ± 0.68 2.74 ± 1.08
Internal Capsule 3.19 ± 0.78 3.30 ± 1.02
Cerebellar white matter 4.56 ± 1.67 5.38 ± 1.83
Non-blood–brain barrier regions   
Subfornical organ 4.02 ± 0.93 4.72 ± 3.10
Median eminence 5.03 ± 1.87 5.44 ± 1.73
Choroid plexus 15.89 ± 6.07 16.66 ± 6.90
  1. k* = (ml/s/g) x 10−4. Values are mean ± S.D of n = 6 saline and 7 quinpirole. Each region of interest was measured in sextuplicate in each rat.