Skip to main content
Figure 1 | BMC Neuroscience

Figure 1

From: Ca2+buffering as a mechanism of short-term synaptic plasticity

Figure 1

[Ca2+] elevation during a 40 Hz train of 1ms-long Ca2+ pulses at 100nm from the Ca2+ source. A: In the presence of a non-cooperative buffer, Ca2+ transients facilitate due to gradual depletion (saturation) of free buffer [6, 7]. B: In the presence of a cooperative buffer, Ca2+ transients depress as a result of increasing exposure of the high-affinity Ca2+ binding site. Both simulations done in 1D geometry (0.5 μm axonal segment), computed using CalC version 7.2 (http://www.calciumcalculator.org)

Back to article page