Figure 1

Shows the simulated microfluidic device (A) and simulated square pulse flow at pts C1 and C2 (B). The responses of the model neuron to changes in Ca++ concentration are shown in panel C. The device in (A) was realized physically, using standard lithography and bonding methods as described in [1]. The Ca++ concentration was recorded and the record was used as an input to the same model neuron, with results indistinguishable from (C).