No acute and direct effect of laminarin on neuronal activity. A. Examples of intracellular recordings of CGCs before or after 30 minutes exposure of the isolated CNS to vehicle (saline) only (top trace) or laminarin (bottom trace). B. Average membrane potential of the CGCs before or 30 minutes post-treatment in vehicle only or laminarin exposed CNS. No significant difference was observed between the two treatment groups. C. Relative action potential frequency of CGCs 15 minutes before and during 30 minutes of exposure to laminarin or vehicle only. No significant difference was observed between the two treatment groups.