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Table 1 Potential LOC689986 protein interaction partners identified by Y2H screens

From: LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex

 

Mouse brain library

Protein

Embryonic

Adult

Chromodomain helicase DNA-binding protein 3

+++

+

Chromodomain helicase DNA-binding protein 4

+++

-

Spectrin beta 2

+++

+

Eukaryotic translation initiation factor 4A-1

+++

-

SUMO1/sentrin specific peptidase 6

++

++

Zinc finger protein 507

++

+

ElaC homolog 2(E.coli)

+

++

  1. The Y2H screens revealed five potential interaction partners common for both the adult and the embryonic mouse brain libraries. Two additional potential binding partners were identified in the embryonic mouse brain library. The potential interaction partners are listed based on the global Predicted Biological Score (PBS®). +++: very high confidence in the interaction (PBS®: A). ++: high confidence in the interaction (PBS®: B), +: good confidence in the interaction (PBS®: C), “-”: not detected.