Figure 4
Microinjection of D 2 R agonist suppressed nociceptive responses recorded in the PFC. A: Time course of procedure is presented. Pre: Pre-quinpirole microinjection. B: The top trace is multiple unit discharges evoked by mechanical stimulation. The second trace represents single unit responses selected by cluster analysis from multi-units. The bottom trace represents a pressure curve. Nociceptive responses were depressed by D2R agonist, quinpirole, microinjection at 10 min. C, D: Mean changes in the duration (C) and frequency (D) of responses are presented. **p<0.01, Error bars represent S.E. n=9.