| |
Young
|
Senior
|
|---|
|
(n=13)
|
(n=17)
|
|---|
|
Demographics
| | |
|
Age (years)
|
22.4 ± 3.0
|
73.0 ±7.6
|
|
Gender (n)
|
9 M, 4 F
|
6 M, 11 F
|
|
Edinburgh Handedness score (/20)
|
15.7 ± 3.4
|
17.7 ± 2.6
|
|
Hand Function
| | |
|
Dexterity
|
RH: 55.5 ± 4.9**
|
RH: 88.5 ± 33.6**
|
|
(GPT in s)
|
LH: 67.5 ± 6.9
|
LH: 100.3 ± 38.9
|
|
Pinch
|
RH: 10.1 ± 2.6**
|
RH: 7.2 ± 1.6
|
|
Strength (kg)
|
LH: 9.1 ± 2.4
|
LH: 6.7 ± 1.7
|
|
Corticomotor excitability a
| | |
|
rMT
|
RH: 61.0 ± 11.3
|
RH:70.1 ± 11.5**
|
|
(% output)
|
LH: 57.6 ± 8.3
|
LH: 65.9 ± 13.0
|
|
MEP amplitude (mV)
|
RH: 5.6 ± 1.8
|
RH: 3.6 ± 1.2
|
|
LH: 5.5 ± 1.8
|
LH: 3.5 ± 1.5
|
|
MEP Latency (ms)
|
RH: 20.2 ± 1.8
|
RH: 21.8 ± 2.1
|
|
LH: 20.1 ± 1.5
|
LH: 21.7 ± 2.3
|
|
cSP duration (ms)
|
RH: 141.5 ± 34.8
|
RH: 115.9 ± 24.2
|
|
LH: 148.9 ± 37.9
|
LH: 115.3 ± 26.0
|
- aAll measures were derived from the hand contralateral to the hemisphere stimulated during the cSP/iSP assessment procedure. TMS data from one senior was incomplete (n=16).
- Abbreviations: GPT Grooved Pegboard Test, RH Right Hand, LH Left Hand, MEP, rMT resting Motor Threshold, Motor Evoked Potential, cSP contralateral Silent Period.
- **Significant right-left differences at p<0.01 in paired t-test comparisons.
