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Figure 3 | BMC Neuroscience

Figure 3

From: Enhanced expression of WD repeat-containing protein 35 (WDR35) stimulated by domoic acid in rat hippocampus: involvement of reactive oxygen species generation and p38 mitogen-activated protein kinase activation

Figure 3

Quantitative examination of WDR35 expression in rat hippocampus following DA administration. (A, B) DA was administered to rats intraperitoneally at various doses. (A) WDR35 mRNA expression in hippocampal RNA preparations at 24 hours after DA administration was analyzed by qRT-PCR and expressed relative to the expression of GAPDH mRNA. (B) WDR35 protein expression in hippocampal homogenates at 24 hours after DA administration was analyzed by western blotting. (C, D) DA (1 mg/kg) was administered to rats intraperitoneally and WDR35 mRNA expression (C) and WDR35 protein expression (D) were determined in hippocampal samples collected at the times indicated after DA administration using the same methods as were used in (A) and (B). *P < 0.05, **P < 0.01 and ***P < 0.001 (n = 4).

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BMC Neuroscience

ISSN: 1471-2202

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