Skip to main content

Table 1 Physiological parameters of rats subjected to ischemia

From: Post-ischemic continuous infusion of erythropoeitin enhances recovery of lost memory function after global cerebral ischemia in the rat

 

Treatment

Before occlusion

After recirculation

After bolus injection

5 h after ischemia

72 h after ischemia

mean arterial pressure (mmHg)

vehicle

123.4 ± 22.1

125.1 ± 21.8

123.7 ± 14.3

  

EPO

111.0 ± 9.7

116.75 ± 15.3

103.3 ± 11.8

  

temperature (°C)

vehicle

 

37.82 ± 0.3

  

38.05 ± 0.5

EPO

 

37.49 ± 0.9

  

37.62 ± 0.5

pCO2 (kPa)

vehicle

4.82 ± 0.96

5.55 ± 1.01

4.73 ± 0.6

5.77 ± 0.41

5.92 ± 0.48

EPO

5.26 ± 1.45

5.75 ± 1.1

5.28 ± 1.89

5.79 ± 0.63

6.35 ± 0.66

pO2 (kPa)

vehicle

17.37 ± 2.57

17.05 ± 3.99

16.67 ± 3.08

16.84 ± 5.33

15.15 ± 2.05

EPO

17.86 ± 2.64

17.69 ± 2.58

17.61 ± 3.05

17.4 ± 4.53

15.23 ± 2.77

pH

vehicle

7.43 ± 0.07

7.34 ± 0.15

7.47 ± 0.06

7.42 ± 0.04

7.44 ± 0.02

EPO

7.43 ± 0.07

7.43 ± 0.06

7.46 ± 0.1

7.43 ± 0.03

7.43 ± 0.05

HCO3-

vehicle

24.32 ± 0.87

26.02 ± 2.72

26.27 ± 1.76

27.1 ± 1.69

29.0 ± 0.7

EPO

25.88 ± 1.39

27.16 ± 1.38

27.68 ± 0.92

27.60 ± 1.05

29.36 ± 1.53

Hb (g/l)

vehicle

159.8 ± 6.61

148.0 ± 11.79

152.0 ± 9.12

145.57 ± 9.45

125.67 ± 4.73*

EPO

149.57 ± 8.1

133.86 ± 9.99

147.0 ± 5.24

141.67 ± 13.49

132.46 ± 27.52

HCT (%)

vehicle

48.9 ± 2

45.4 ± 3.5

46.6 ± 2.8

44.6 ± 2.8

38.7 ± 1.5*

EPO

45.0 ± 3.2

41.8 ± 2.6

44.2 ± 3.1

42.7 ± 4.5

42.3 ± 5.4

glucose (mmol/l)

vehicle

5.88 ± 2.7

    

EPO

7.05 ± 1.6

    
 

treatment

before occlusion

   

7 days after ischemia

body weight (g)

vehicle

332.0 ± 8.3

   

335.1 ± 17.5

EPO

345.0 ± 18.3

   

332.9 ± 18.9

  1. Data are presented as means ± standard deviation at the time of recirculation. Statistical differences are indicated. No indications are given if no difference was observed between the treatment groups. *p = 0.0002 vs vehicle treatment before occlusion.