VGLUT1 | VGLUT2 | VGLUT3 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Ipsilateral side | Controlateral side | Ipsilateral side | Controlateral side | Ipsilateral side | Controlateral side | |||||||
A | Controls | 6-OHDA | Controls | 6-OHDA | Controls | 6-OHDA | Controls | 6-OHDA | Controls | 6-OHDA | Controls | 6-OHDA |
CPu | 51,35 (±3,2) | 53,33 (±1,9) | 48,78 (±3,4) | 52,59(±1,7) | 20,15 (±2,38) | 12,64*(±1,5) -37% | 19,76 (±2,3) | 13,38*(±0,6) -33% | 16, 65(±0,8) | 18,15 (±1,7) | 15,37 (±0,8) | 16, 33 (±3,1) |
PM Cx | 55,54 (±3,3) | 48,3 (±2,1) | 55,81 (±2,9) | 48,07 (±2,8) | 18,56 (±1,7) | 10,93*(±0,6) -42% | 18,5 (±2,1) | 11,12*(±0,6) -40% | 14,34 (±0,9) | 13,09 (±2,4) | 14,39 (±0,9) | 13, 02 (±2,5) |
SS Cx | 45,93 (±3) | 35,37 (±1,6) | 45,93 (±1,6) | 38,93 (±1,6) | 15,79 (±1,81) | 9,22*(±0,4) -42% | 16,44 (±1,8) | 10,57*(±0,6) -36% | 12,01 (±0,6) | 10,28 (±2,1) | 12,89 (±0,7) | 11,63 (±2,4) |
Acb | 54,15 (±2,8) | 63,43 (±2,8) | 51,52 (±3,6) | 59,65 (±3,1) | 22,55 (±2,7) | 13,56*(±2,1) -40% | 22,14 (±2,6) | 13,91*(±2,1) -47% | 18,84 (±0,9) | 23,33 (±1,1) | 19,04 (±1,1) | 23 (±1,2) |
Thalamus | 41,18 (±3,4) | 34,15 (±1,7) | 41,86 (±3,3) | 32,47 (±1,1) | 16,83 (±2,3) | 8,85*(±0,4) -48% | 17,49 (±2,4) | 9,05*(±0,7) -48% | 11,38 (±0,5) | 9,85 (±1,3) | 11,43 (±0,5) | 9,79 (±1,1) |
STN | 21,13 (±2,7) | 23, 56 (±4,6) | 19,25 (±2,5) | 20,65 (±4,2) | 16,83 (±2,1) | 7,66*(±1,3) -55% | 15,53 (±2,3) | 9,32*(±0,5) -40% | ND | ND | ND | ND |
GP | ND | ND | ND | ND | 12,78 (±1,9) | 7,97(±1) | 13,39 (±1,7) | 8,83 (±1,1) | ND | ND | ND | ND |
SNr | ND | ND | ND | ND | 51,1 (±2,4) | 11,26*(±0,3) -25% | 15,76 (±2,2) | 11,39*(±0,5) -28% | ND | ND | ND | ND |
Ipsilateral side | Controlateral side | Ipsilateral side | Controlateral side | Ipsilateral side | Controlateral side | |||||||
B | 6-OHDA | 6-OHDA + STN-HFS | 6-OHDA | 6-OHDA + STN-HFS | 6-OHDA | 6-OHDA + STN-HFS | 6-OHDA | 6-OHDA + STN-HFS | 6-OHDA | 6-OHDA + STN-HFS | 6-OHDA | 6-OHDA + STN-HFS |
CPu | 53,33 (±1,8) | 65,07*(±3,4) +22% | 52,59 (±1,7) | 64,43(±3,2) +23% | 12,64 (±1,5) | 17,81*(±1,4) +41% | 13,38 (±0,6) | 17,61*(±1,8) +32% | 18,15 (±1,7) | 26,13*(±2,9) +44% | 16,33 (±3,1) | 24,88*(±1,8) +53% |
PM Cx | 48,3 (±2,2) | 63,08*(±3,3) +31% | 48,07 (±2,8) | 64, 79*(±3,5) +35% | 10,93 (±0,6) | 16,93*(±1,6) +55% | 11,12 (±0,6) | 16,86*(±1,8) +52% | 13,09 (±2,4) | 20*(±1,9) +53% | 13,02 (±2,5) | 16,62*(±1,7) +51% |
SS Cx | 35,75 (±1) | 54,25*(±3,8) +52% | 38,93 (±1,6) | 55,08*(±3,8) +41% | 9,22 (±0,4) | 14,03*(±1,4) +52% | 10,57 (±0,6) | 13,38*(±1,6) +27% | 10,28 (±2,1) | 20,44*(±2,1) +99% | 11,63 (±2,4) | 16,78*(±1,4) +44% |
Acb | 63,43 (±2,8) | 65,39 (±3,9) | 59,65 (±4,1) | 65,06 (±4,1) | 13,56 (±2,1) | 20,25*(±1,3) +49% | 13,91 (±2,1) | 18,78*(±1,2) +35% | 23,23 (±1,1) | 31,7* (1,2) +36% | 23 (±1,2) | 31,89*(±1,2) +38% |
Thalamus | 34,15 (±1,7) | 48,1*(±3,8) +41% | 32,47(±1,1) | 46,37 (±3,6) +43% | 8,85 (±0,4) | 14,63*(±1,6) +65% | 9,05 (±0,7) | 13,5*(±1,5) +449% | 9,85 (±1,3) | 20,3*(±1,6) +106% | 9,79 (±1,1) | 19,38*(±2,5) +98% |
STN | 23,56 (±4,6) | 17,78 (±2,6) | 20,65 (±4,2) | 19,34 (±3) | 7,66 (±1,3) | 14,79*(±1,5) +93% | 9,32 (±0,5) | 15,94*(±1,9) +71% | ND | ND | ND | ND |
GP | ND | ND | ND | ND | 7.97 (±1) | 10,18 (±0,9) | 8,83 (±1,1) | 9,61 (±1) | ND | ND | ND | ND |
SNr | ND | ND | ND | ND | 11,26 (±0,3) | 15,84*(±1,3) +41% | 11,39 (±0,5) | 16,64*(±1,4) +46% | ND | ND | ND | ND |