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Table 2 Summary of the α-syn species detected by MS in brain lysates from two hA30Pα-syn mice with functional parkin (column # 1–2) and three hA30Pα-syn mice lacking both parkin alleles (column # 3–5)

From: Parkin depletion delays motor decline dose-dependently without overtly affecting neuropathology in α-synuclein transgenic mice

  

hA30Pα-syn+/+

parkin-/-; hA30Pα-syn+/+

  

# 1

# 2

# 3

# 4

# 5

Human

α-syn

+ +

+ +

+ +

+ +

+ +

 

α-synD135

+ +

+ +

-

+

+ +

 

α-synY133

-

-

-

-

-

Mouse

α-syn

+ +

+ +

+

+

+ +

 

α-synD135

-

-

-

-

-

 

α-synY133

-

-

-

-

-

  1. -: not detected; +: identified with a probability between 80% and 94%; ++: identified with a probability >95%.