Skip to main content

Table 2 Summary of the α-syn species detected by MS in brain lysates from two hA30Pα-syn mice with functional parkin (column # 1–2) and three hA30Pα-syn mice lacking both parkin alleles (column # 3–5)

From: Parkin depletion delays motor decline dose-dependently without overtly affecting neuropathology in α-synuclein transgenic mice

   hA30Pα-syn+/+ parkin-/-; hA30Pα-syn+/+
   # 1 # 2 # 3 # 4 # 5
Human α-syn + + + + + + + + + +
  α-synD135 + + + + - + + +
  α-synY133 - - - - -
Mouse α-syn + + + + + + + +
  α-synD135 - - - - -
  α-synY133 - - - - -
  1. -: not detected; +: identified with a probability between 80% and 94%; ++: identified with a probability >95%.