Figure 3From: Targeted over-expression of endothelin-1 in astrocytes leads to more severe brain damage and vasospasm after subarachnoid hemorrhageVasospasm analysis and NOS expressions in MCA after subarachnoid hemorrhage. (A) Representative pictures show the histological analysis of MCA. Vasospasm is observed in both Ntg and GET-1 brain after SAH when compared to that of their sham group (n = 5). Histogram shows the arterial diameter measurement of MCA in Ntg and GET-1 after SAH. (*P < 0.05, Mann-Whitey test; n = 5 for Ntg and GET-1 mice). Expression of NOS in MCA after SAH. Representative photos shows the (B) nNOS, (C) eNOS and (D) p-eNOS expressions of sham and SAH of MCA in Ntg and GET-1 brain. Arrowheads show the expression of nNOS (tunica adventitia) and eNOS/p-eNOS (tunica intima), (n = 4 for each group of mice). Histograms show the quantification results (relative value in percentage) of immunocytochemistry of sham and SAH of Ntg and GET-1 MCA sections. (*P < 0.05, **P < 0.01, ANOVA followed by Bonferroni’s test; n = 4 for each group of mice).Back to article page