Figure 3From: MAPK signaling pathway regulates cerebrovascular receptor expression in human cerebral arteriesA. Concentration response curves elicited by cumulative application of U46619 in human cerebral arteries incubated for 48 h, human cerebral arteries incubated for 48 h with the MEK1/2 inhibitor U0126 (5 μM) and control human arteries. Data are expressed as mean ± s.e.m. B. Sections from the human cerebral artery showing TP receptor immunoreactivity in the smooth muscle cell layer. C. Expression of TP protein levels in human cerebral arteries incubated for 48 h with or without the MEK1/2 inhibitor U0126 (5 μM) and control human arteries. Data are expressed as percentage of fresh and given as mean ± s.e.m. *P<0.05, ** P<0.01.Back to article page