Figure 6
From: Phenotyping dividing cells in mouse models of neurodegenerative basal ganglia diseases
Regional quantification of neuronal, microglial, astroglial, and oligodendroglial cells derived from dividing progenitors in control and striatal line mutant mice. Graphs showing the number of double-positive NeuN+/BrdU+, Iba1+/BrdU+, S100β+/BrdU+ and Olig2+/BrdU+ cells at specific sites relative to bregma in the M1 motor cortex (A-D), striatum (E-H) and periventricular (I-L) regions of the brain of mice belonging to the striatal line and control mice injected for 2 weeks with BrdU+ at 4 weeks of age and killed at age 8 weeks. There was a significant increase in the number of Iba1+/BrdU+ cells in the striatum and periventricular regions (both P< 0.001) in striatal mutant relative to control mice.