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Figure 3 | BMC Neuroscience

Figure 3

From: Probabilistic model for individual assessment of central hyperexcitability using the nociceptive withdrawal reflex: a biomarker for chronic low back and neck pain

Figure 3

Scheme of the proposed probabilistic prediction model. (A) Given a query subject X q  ∈ TE, a set of EMG signals F qj , j = 1 , 4 ¯ are obtained as a response to repeated electrical stimulation of ten sites on the sole of the foot. (B) A probability distribution histogram P qj is constructed from each signal F qj (or combination of signals from multiple sites) to be used as classification feature. (C) The signal F qj is labelled p (for patient) or h (for healthy), depending on the distances d qj to the closest neighbouring histograms P i , derived from the set of training subjects {X i  ∈ TR}. (D) The final prediction for the subject X q is carried out based on the labels l qj derived from the individual assessment of all four signals. Query subjects X q  ∈ V were used instead for all validation procedures (site combination and training set selection).

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