Figure 4

Sex difference in hindbrain gene expressions after exposure to synthesized pheromone component in sea lamprey. Exposure to 10^-10 M 3kPZS decreased GAP50 mRNA (2 h, 8 h, 24 h, and 48 h, p < 0.05) and JNK mRNA (2 h, 4 h, 8 h, and 24 h, p < 0.05) concentrations in the brain stem of immature females (A-C). Exposure to 3kPZS increased GAP49 & 58, lGnRH-III, Jun and JNK mRNA concentrations in the brain stem of immature males (D-E). The following data points are statistically different from 0 h control (p < 0.05). D. lGnRH-III: 2 h & 48 h; Jun: 48 h; JNK: 2 h, 8 h, 24 h & 48 h. E. GAP58: 48 h; lGnRH-III: 48 h; Jun: 2 h & 48 h; JNK: 2 h, 4 h & 48 h. F. GAP49: 8 h & 24 h; GAP58: 48 h; lGnRH-III: 8 h & 48 h; JNK: 2 h & 8 h.