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Table 3 Schizophrenia gene set network properties

From: Meta-analysis of gene coexpression networks in the post-mortem prefrontal cortex of patients with schizophrenia and unaffected controls

 

Up-regulated (25)

Down-regulated (69)

 

CTL

SZ

CTL

SZ

Node degree

    

Mean

63.9

83.5

127.4

106.2

Non-interacting nodes

2

2

7

3

Edges (within gene set)

12

23

129

144

Shortest Path

    

Mean

3.28

3.14

3.31

3.48

Random gene set comparison

    

Z-score

−0.58

−0.91

3.15

4.46

p-value

0.23

0.15

0

0

Cluster Coefficient

    

Mean

0.35

0.38

0.32*

0.27*

Random gene set comparison

    

Z-score

1.11

2.47

1.51

−0.607

p-value

0.14

0.005

0.06

0.28

  1. *Difference is significant between CTL and SZ at p = 0.05.
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BMC Neuroscience

ISSN: 1471-2202

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