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Figure 3 | BMC Neuroscience

Figure 3

From: PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus

Figure 3

Temporal curve of MKP-7 protein levels and activities during different reperfusion times following cerebral ischemia. Proteins were extracted and measured using antibodies against MKP-7. MKP-7 was purified by immunoprecipitation, and its activity was measured using an alkaline phosphatase assay. A: Time curve of MKP-7 levels during different reperfusion times (15 min, 1, 2, 4, 6 and 24 h) following 10 min of ischemia. B: Temporal curve of MKP-7 activity after different reperfusion times (15 min, 1, 2, 4, 6 and 24 h) following 10 min of ischemia. OD data are presented as means ± SEM (n = 4) and expressed as magnitudes of the alteration versus sham control or control [*P < 0.05 versus sham control].

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