Figure 1
The linear information rate, I L (g;s), which represents the information per unit time available to an optimal linear decoder that estimates a rate-coded presynaptic signal, s(t), by observing a postsynaptic conductance, g(t). The linear information rate is plotted as a function of the peak frequency, f s , of the signal. When stochastic vesicle dynamics are ignored (dashed red line), I L (g;s) is independent of f s [3, 4]. When stochastic vesicle dynamics are accounted for (solid blue line), information transfer is reduced and high-frequency signals are transferred more reliably than low-frequency signals.