Figure 1
From: Schwann cells migrate along axons in the absence of GDNF signaling
Scheme showing the experimental setup of the SCG SC migration assay. SCGs were explanted and put onto/in a collagen-gel. NGF treatment facilitates axonal growth (B) into the collagen matrix. Axons elongate further over the time (C) and SCs (blue) can be appreciated migrating along the axons from the SCG explant to the periphery as depicted in the close up (D). At the endpoint of analyses the gel was shrunk to two dimensions to enable the measurement from the border of the SCG explant to the leading SC (red dotted lines in D).