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Table 5 Measurement of sAPPα in mouse CSF

From: New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: preclinical and clinical applications in Alzheimer’s disease

Mice

r-sAPPα (ng/ml)

h-sAPPα (ng/ml)

Wild-type (5)

137 ± 17

0

3xTg AD (7)

105 ± 8#

34 ± 6

  1. CSF samples (2–5 μl) were collected from wild type or 3xTg AD mice and 1/5 or 1/10 dilutions of the CSF were tested in the r-sAPPα and in the h- sAPPα assays.#: This value includes 23% of h- sAPPα (see Figure 2C).
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BMC Neuroscience

ISSN: 1471-2202

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