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Figure 7 | BMC Neuroscience

Figure 7

From: Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea

Figure 7

Erythropoietin treatment prevents IH-induced anxiety in mice. (A). Mice exposed to IH and treated with vehicle (IH-C) spend significantly less time in the open arm of the elevated plus maze compared to IH-EPO, RA-EPO, or RA-C mice (n = 18/experimental group;*-p < 0.001). (B). A reduced number of closed-arm entries emerged in mice exposed to IH and treated with vehicle (n = 18/experimental group;* - p < 0.001). (C). Time spend in the Center Area was increased in mice exposed to IH and treated with vehicle (n = 18/experimental group;* - p < 0.001).

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