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Table 4 Functional Activations for High-Calorie, Low-Calorie and Non-Food Object Contrasts Post-Treatment vs. Baseline (Pre-Treatment) in Obese Endometrial Cancer Patients in a 16-Session Behavioral Lifestyle Intervention

From: Reduction in neural activation to high-calorie food cues in obese endometrial cancer survivors after a behavioral lifestyle intervention: a pilot study

     Brain Region (Hemisphere) Pre-Meal (Fasted) Post-Meal (Fed/Satiated)
Peak Voxel Peak Voxel
x y z Cluster Size* t x y z Cluster Size* t
POST < PRE TREATMENT High Calorie vs. Low Calorie Food
     No regions survived threshold           
  High Calorie vs. Non-Food Object
     Superior Frontal Gyrus (BA = 6) 38 39 30 416 -4.72      
     Lateral Globus Pallidus       20 -13 6 972 -9.45
     Cingulate Gyrus (BA = 31)       -9 -23 34 968 -6.63
     Thalamus       -14 -24 5 738 -5.63
     Posterior Cingulate (BA = 29)       -8 -45 16 583 -6.52
     Precuneus (BA = 31)       -16 -44 30 811 -5.85
     Claustrum       37 -6 6 911 -6.62
  Low Calorie vs. Non-Food Object
     Insula (Bilateral; L; BA = 13)       38 -22 11 613 -5.44
     Insula (Bilateral; R; BA = 13)       -40 -13 14 691 -6.64
     Precentral Gyrus (BA = 4)       -52 -12 24 963 -10.6
     Middle Temporal Gyrus (BA = 39)       -39 -50 6 568 -4.73
POST > PRE TREATMENT High Calorie vs. Low Calorie Food
     Superior Temporal Gyrus (BA = 22)       -48 11 -5 758 5.72
     Superior Frontal Gyrus (BA = 10)       21 63 27 607 5.90
  High Calorie vs. Non-Food Object
     No regions survived threshold           
  Low Calorie vs. Non-Food Object           
     No regions survived threshold           
  1. x, y, z = coordinates in Talairach space; t statistic for peak voxel; *Cluster size is reported in mm3. Results are whole brain cluster corrected for multiple comparisons; threshold α < 0.05 (min cluster size: 15–36 voxels).