Post-Treatment Compared to Baseline for Low-Calorie vs. Non-Food Post-Meal Contrast in Obese Endometrial Cancer Patients Receiving a 16 Session/6-month Behavioral Lifestyle Intervention. A) Main effect (coronal view) of significant (whole brain cluster corrected, p < 0.05) decreased activation (blue) observed post-treatment (PostTx) compared to baseline (PreTx) for high-calorie vs. non-food objects in the fed state: a) insula (bilateral); b) postcentral gyrus; and, c) middle temporal gyrus. B) Mean BOLD effect (mean beta value) at PostTx (blue) and PreTx (red) by calorie condition. In these regions, low-calorie vs. non-food contrasts were significantly (p < 0.001) lower PostTx vs. PreTx (hatched blue vs. hatched red) (see text for details).