Table 1 Radioligand binding to Drosophila nAChR subunit combinations
Subunit combination | [125I]-α-BTX Binding | [3 H]-epibatidine binding | ||
|---|---|---|---|---|
- RIC3 | + RIC3 | - RIC3 | + RIC3 | |
Dα5 | – | – | – | – |
Dα5/Dα1 | – | – | – | – |
Dα5/Dα2 | – | – | – | – |
Dα5/Dα3 | – | – | – | – |
Dα5/Dα4 | – | – | – | – |
Dα5/Dα6 | – | + | – | – |
Dα5/Dα7 | – | – | – | – |
Dα5/Dβ1 | – | – | – | – |
Dα5/Dβ2 | – | – | – | – |
Dα5/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα2 | – | – | – | – |
Dα5/Dα1/Dβ1 | – | – | – | – |
Dα5/Dα1/Dβ2 | – | – | – | – |
Dα5/Dα1/Dβ3 | – | – | – | – |
Dα5/Dα2/Dβ1 | – | – | – | – |
Dα5/Dα2/Dβ2 | – | – | – | – |
Dα5/Dα2/Dβ3 | – | – | – | – |
Dα5/Dα3/Dβ1 | – | – | – | – |
Dα5/Dα3/Dβ2 | – | – | – | – |
Dα5/Dα3/Dβ3 | – | – | – | – |
Dα5/Dα4/Dβ1 | – | – | – | – |
Dα5/Dα4/Dβ2 | – | – | – | – |
Dα5/Dα4/Dβ3 | – | – | – | – |
Dα5/Dα6/Dα7 | – | – | – | – |
Dα5/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dβ1/Dβ3 | – | – | – | – |
Dα5/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα2/Dβ1 | – | – | – | – |
Dα5/Dα1/Dα2/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα3/Dβ1 | – | – | – | – |
Dα5/Dα1/Dα3/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα3/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα4/Dβ1 | – | – | – | – |
Dα5/Dα1/Dα4/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα4/Dβ3 | – | – | – | – |
Dα5/Dα2/Dα3/Dβ1 | – | – | – | – |
Dα5/Dα2/Dα3/Dβ2 | – | – | – | – |
Dα5/Dα2/Dα3/Dβ3 | – | – | – | – |
Dα5/Dα2/Dα4/Dβ1 | – | – | – | – |
Dα5/Dα2/Dα4/Dβ2 | – | – | – | – |
Dα5/Dα2/Dα4/Dβ3 | – | – | – | – |
Dα5/Dα3/Dα4/Dβ1 | – | – | – | – |
Dα5/Dα3/Dα4/Dβ2 | – | – | – | – |
Dα5/Dα3/Dα4/Dβ3 | – | – | – | – |
Dα5/Dα6/Dα7/Dβ1 | – | – | – | – |
Dα5/Dα6/Dα7/Dβ2 | – | – | – | – |
Dα5/Dα6/Dα7/Dβ3 | – | – | – | – |
Dα5/Dβ1/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dβ1 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα2/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα3/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα4/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα2/Dα3/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα2/Dα4/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα3/Dα4/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα2/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα3/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα4/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dβ1/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα2/Dα3/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα2/Dα4/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα2/Dβ1/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα3/Dα4/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα3/Dβ1/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dα4/Dβ1 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dα4/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dα4/Dβ3 | – | – | – | – |
Dα5/Dα6/Dα7/Dβ1/Dβ2/Dβ3 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dα4/Dα6/Dα7/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dα4/Dα6/Dα7/Dβ1/Dβ2 | – | – | – | – |
Dα5/Dα1/Dα2/Dα3/Dα4/Dα6/Dα7/Dβ1/Dβ2/Dβ3 | – | – | – | – |