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Table 1 Top 25 highly-expressed genes in AMC based on fold change. Both MATLAB and GeneSpring analysis are represented

From: Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain

  Genes from MATLAB analysis   Genes from Genespring analysis
Gene Symbol Gene Title Fold Change Function Gene Symbol Gene Title Fold Change Function
Sla Src-like adaptor 73.34 protein binding LRRGT00193 Unknown 574.79 Unknown
Dpysl3 dihydropyrimidinase-like 3 31.01 nervous system development Rnf152 ring finger protein 152 35.04 Unknown
Sox4 SRY (sex determining region Y)-box 4 28.33 pro-B cell differentiation Syncrip Synaptotagmin binding, cytoplasmic RNA interacting protein 26.62 mRNA processing
Rprm reprimo, TP53 dependent G2 arrest mediator candidate 19.13 cell cycle arrest Chst8 carbohydrate (N- acetylgalactosamine 4–0) sulfotransferase 8 26.17 sulfur metabolic process
Satb2 SATB homeobox 2 18.05 negative regulation of transcription Rpl28 ribosomal protein L28 19.32 translation
Dcx Doublecortin 16.64 neuronmigration Slc16a7 solute carrier family 16, member 7 (monocarboxylic acid transporter 2) 18.85 transport
Crmp1 collapsin response mediator protein 1 15.50 neuron development Crmp1 collapsin response mediator protein 1 18.54 neuron development
Syt16 synaptotagmin XVI 13.53 protein binding LOC100158225 hypothetical protein LOC100158225 17.44 Unknown
Cct8 chaperonin containing Tcp1, subunit 8 (theta) 13.53 protein folding Bmp2 bone morphogenetic protein 2 16.43 ossification
RGD1310352 similar to HTGN29 protein; keratinocytes associated transmembrane protein 2 13.42 Unknown Dcx doublecortin 15.26 neuron migration
Appbp2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 13.28 Transport Mab21l1 mab-21-like 1 (C. elegans) 14.54 positive regulation of cell proliferation
Cxcr4 chemokine (C-X-C motif) receptor 4 12.76 ameboidal cell migration Hmgb3 high mobility group box 3 14.14 negative regulation of myeloid cell differentiation
Ect2 epithelial cell transforming sequence 2 oncogene 12.50 cell morphogenesis Baz1a bromodomain adjacent to zinc finger domain, 1A 13.89 protein binding
Hmgb3 high mobility group box 3 12.47 negative regulation ofB cell differentiation Sox4 SRY (sex determining region Y)-box 4 13.43 pro-B cell differentiation
Hs3st5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 12.32 protein amino acid sulfation LOC688455 hypothetical protein LOC688455 12.93 Unknown
Cfl2 cofilin 2, muscle 12.21 protein binding Cxcr4 chemokine (C-X-C motif) receptor 4 12.92 ameboidal cell migration
Tnc Tenascin C 11.93 negative regulation of cell adhesion Spint2 serine peptidase inhibitor, Kunitz type, 2 12.49 serine-type endopeptidase inhibitor activity
Nap1l3 nucleosome assembly protein 1-like 3 10.88 nucleosome assembly Zfml zinc finger, matrin-like 12.20 nucleic acid binding
Mex3b mex3 homolog B (C. elegans) 10.78 RNA binding Nradd neurotrophin receptor associated death domain 11.65 signal transduction
Smarca1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 10.72 brain development Bcl7c B-cell CLL/lymphoma 7 C 11.44 Unknown
Sh3bgrl SH3 domain binding glutamic acid-rich protein like 9.74 Unknown Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 11.43 multicellular organismal development
Ascc3l1 Activating signal cointegrator 1 complex subunit 3-like 1 9.58 RNA splicing Mtus1 mitochondrial tumor suppressor 1 11.12 cell cycle
Bex4 brain expressed gene 4 9.50 Nucleus Adfp Adipose differentiation related protein 10.85 response to organic cyclic substance
Fam164a family with sequence similarity 164, member A 9.49 Unknown Ttk Ttk protein kinase 10.65 protein amino acid fig7 phosphorylation
LOC294446 similar to Myristoylated alanine-rich C-kinase substrate (MARCKS) (ACAMP-81) 9.44 calmodulin binding Lrrc20 leucine rich repeat containing 20 10.63 protein binding
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