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Table 1 Major brain activations in 32 pain non-human animal studies

From: Common brain activations for painful and non-painful aversive stimuli

Rank order: Pain (32 studies)
Area Studies reporting activation Percentage
Cingulate 15 47%
Thal 14 44%
Sens 13 41%
Hyp 12 38%
Amyg 9 28%
PAG 9 28%
DS 9 28%
Motor 7 22%
Ins 7 22%
Hipp/parahipp 6 19%
NTS 5 16%
IC 5 16%
LC, PBN, Pretectal area, SC, Septal area 4 each 13%
Hab, NAc, Raphe, Piriform, PFC(IL/PL)/OFC, Visual ctx 3 each 9%
Aud ctx, BNST, Cerebellum, Retrosplenial 2 each 6%
Red n 1 3%
  1. Results are ordered by the number of studies reporting specific activations; percent of studies reporting activations is used for comparative illustration. For individual study details and inter-study comparisons, see Additional file 1: Table S2A.