Table 1 Major brain activations in 32 pain non-human animal studies
From: Common brain activations for painful and non-painful aversive stimuli
Rank order: Pain (32 studies) | ||
|---|---|---|
Area | Studies reporting activation | Percentage |
Cingulate | 15 | 47% |
Thal | 14 | 44% |
Sens | 13 | 41% |
Hyp | 12 | 38% |
Amyg | 9 | 28% |
PAG | 9 | 28% |
DS | 9 | 28% |
Motor | 7 | 22% |
Ins | 7 | 22% |
Hipp/parahipp | 6 | 19% |
NTS | 5 | 16% |
IC | 5 | 16% |
LC, PBN, Pretectal area, SC, Septal area | 4 each | 13% |
Hab, NAc, Raphe, Piriform, PFC(IL/PL)/OFC, Visual ctx | 3 each | 9% |
Aud ctx, BNST, Cerebellum, Retrosplenial | 2 each | 6% |
Red n | 1 | 3% |