Figure 5

QRT-PCR analysis of atf3 , btg2 , gadd45β , and gadd45γ and bdnf expression in uninfected hippocampal neurons and in neurons infected with rAAV-hrGFP, rAAV-CREB and rAAV-mCREB. Gene expression analyses were done on DIV 9 (A) and DIV 10 (B), which correspond to five days and six days, respectively, post-infection. Bars represent SEM (n = 3). Statistical significance was determined by One-way ANOVA, Bonferroni post hoc test, statistically significant differences are indicated with an asterisk (***p < 0.001, **p < 0.01, *p < 0.05).