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Figure 8 | BMC Neuroscience

Figure 8

From: NF-κB p50 subunit knockout impairs late LTP and alters long term memory in the mouse hippocampus

Figure 8

Basal synaptic transmission in CA1 hippocampal slices. A: Input–output relations were measured as a function of increased voltage. We found no significant difference between p50−/− and p50+/+ strains (P = 0.109) when assessing input–output curves. However, we did find a significant main effect of voltage on EPSP amplitude response (P < 0.001). In addition, we found a significant interaction between strain and stimulation voltage (P = 0.004). B: We also compared paired-pulse responses, an indicator of presynaptic function, and found no significant difference (P = 0.34) between strains using an interstimulus interval of 50 ms

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