Figure 1From: NF-κB p50 subunit knockout impairs late LTP and alters long term memory in the mouse hippocampusEscape latency during Morris water maze testing. Escape latency was measured in p50 mice during the acquisition phase, where both groups significantly decreased (P < 0.001) their escape latency times over 7 days of testing (p50+/+: from mean 36 s to 20 s; p50−/− mean 46 s to 14 s), but there was no statistical difference (P = 0.39) between p50−/− and p50+/+ mice over the 7 day period. A trend is seen on day 3 where p50−/−mice show shorter escape times.Back to article page