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Table 1 Clinical parameters of EAE experiments in SJL/J mice and DA rats (*, p < 0

From: Inhibition of SLPI ameliorates disease activity in experimental autoimmune encephalomyelitis

  Incidence Mortality Disease onset [d] ± StdDev Cumulative score ± StdDev Mean maximal score ± StdDev
SLPI immunization in passive EAE of SJL/J mice      
SLPI-immunized mice 10/10 0/10 23.0 ± 4.6 * 8.9 ± 4.6 * 2 ± 0.5
OVA-immunized mice 7/7 0/7 17 ± 2.8 21.4 ± 7.5 2.6 ± 0.7
SLPI immunization in active EAE of DA rats      
SLPI-immunized rats 7/8 1/8 20.9 ± 10.8 21.2 ± 19.3 2.8 ± 2.0 *
OVA-immunized rats 8/8 3/8 13.8 ± 1.8 30.7 ± 9.3 4.5 ± 0.8
SLPI administration in active EAE of SJL/J mice      
SLPI-treated mice 6/7 1/7 11.1 ± 2.4 * 29.7 ± 15.3 3.1 ± 1.5
saline-treated mice 5/5 0/5 15.2 ± 4.4 19.8 ± 5.7 2.8 ± 0.4