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Table 2 Morphometric parameters of proximal and distal segments of the sural nerve fascicles of male and female WKY and SH

From: Sural nerve involvement in experimental hypertension: morphology and morphometry in male and female normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR)

  Female
WKY
Male
WKY
Female
SHR
Male
SHR
Female
WKY
Male
WKY
Female
SHR
Male
SHR
  Proximal Segments     Distal Segments  
FA (μm2) 49096 ± 3140 52479 ± 3052 51596 ± 2484 54504 ± 3062 38162 ± 2635* 41188 ± 3998 44956 ± 4812* 50144 ± 4272
Fascicle Ø (μm) 193 ± 16 181 ± 22 205 ± 14 184 ± 15 89 ± 4* 113 ± 20 146 ± 9*# 155 ± 15#
MF number 871 ± 25 831 ± 47 889 ± 36 884 ± 33 746 ± 47* 725 ± 53 690 ± 47* 688 ± 45
MFD (fibers/μm2) 18469 ± 1072 15986 ± 724 17454 ± 715 16541 ± 647 19849 ± 821 18119 ± 1059 16370 ± 972# 14770 ± 1586#
SCN number 40 ± 3 42 ± 5 35 ± 4 35 ± 2 33 ± 2 35 ± 3 35 ± 5 27 ± 2
SCND (nuclei/μm2) 843 ± 58 810 ± 100 731 ± 84 666 ± 48 906 ± 83 889 ± 60 800 ± 68# 576 ± 78#
MF occupancy (%) 38.79 ± 1.46 36.90 ± 1.65 40.10 ± 1.82 41.30 ± 2.96 40.15 ± 1.56 39.80 ± 1.99 35.75 ± 1.62 35.09 ± 3.01
CP occupancy (%) 0.96 ± 0.26 0.90 ± 0.22 0.40 ± 0.13 0.55 ± 0.09 0.71 ± 0.19 0.69 ± 0.13 0.18 ± 0.06# 0.28 ± 0.12#
  1. Data expressed as mean ± standard error of mean (SEM). FA = fascicle area, Ø = diameter, MF = myelinated fiber, MFD = myelinated fiber density, SCN = Schwann cell nuclei, SCND = Schwann cell nuclei density, CP = capillary. * indicates differences between proximal and distal segments (paired Student's t-test p < 0.05); # indicates differences between WKY and SHR (unpaired Student's t-test, p < 0.05)