Figure 3
From: Developmental changes in human dopamine neurotransmission: cortical receptors and terminators
(A) DRD2S (p < 0.001) and (B) DRD2L (p = 0.003) qPCR mRNA results. (A) Neonates (p < 0.001), infant, and toddler groups (p < 0.01) had greater DRD2S mRNA than that of school age, adolescent, young adult & adult age groups. (B) DRDL mRNA followed a similar developmental pattern with the neonatal age group having the higher levels of DRD2L mRNA compared to school age (p = 0.050), adolescent (p < 0.001), young adult (p = 0.006), and adult age groups (p = 0.001). The toddler group had greater DRD2L mRNA than adolescents (p = 0.009), young adults (p = 0.041), and adults (p = 0.012). *** p ≤ 0.001, ** p ≤ 0.01, * p ≤ 0.05.