Individual differences in resting motor threshold (RMT), mean MEP amplitude and mean MEP latency depending on the direction of the induced current in M1-HAND (Experiment 1, n = 10 for MEP and latency, n = 7 for RMT). MEP were recorded from relaxed left APB muscle. MEPs were evoked with single-pulse TMS using a half-sine wave stimulus and a suprathreshold stimulus intensity to elicite mean MEP amplitude of 0.5 mV (SI0.5mV). (A) The resting motor threshold expressed in % of MSO was consistently lower for PA as opposed to AP stimulation. (B) Mean MEP latency of left APB was consistently shorter for PA as opposed to AP stimulation. (C) Mean MEP amplitudes of left APB were consistently larger for PA stimulation. PA: Half-sine wave stimulus inducing a posterior-anterior current in M1-HAND, AP: Half-sine wave stimulus inducing an anterior-posterior current in M1-HAND. Error bars indicate mean ± standard error of the mean.