Figure 9
From: Kalrnplays key roles within and outside of the nervous system
Neuromuscular junctions are abnormal in KalSRKO/KOmice. A.Individually teased fixed anterior tibialis muscles of adult WT and KalSRKO/KO male and female mice were incubated with fluorescently tagged α-BTX to visualize postsynaptic AChR clusters. B. Neuromuscular junctions were categorized as normal (pretzel-shaped) or open (broken) and the percentage of the junctions categorized as normal was calculated for three WT and three KalSRKO/KO mice; bars show data from a single mouse. KalSRKO/KO mice have a lower fraction of intact pretzel shaped junctions (t-test; p=0.044) and a larger fraction of broken junction shapes (t-test; p=0.044).