| | |
RMP
|
Vmax
|
Depolarization amplitude
|
Current threshold
|
|---|
| |
n
|
(mv)
|
(mV/ms)
|
(mV)
|
(pA)
|
|---|
|
Day 0
|
22
|
−34.9 ± 1.4
|
20.1 ± 0.9
|
32.1 ± 1.6
|
n/a
|
|
Day 9
|
15
|
−43.2 ± 1.5*
|
23.2 ± 1.2
|
45.0 ± 2.9*
|
n/a
|
|
Day 21
| | | | | |
|
Without AP
|
30
|
−45.4 ± 2.1*
|
28.5 ± 3.5*
|
46.1 ± 4.7*
|
n/a
|
|
Day 21
| | | | | |
|
with AP
|
25
|
−56.1 ± 1.6*#$
|
136.1 ± 13.7*#$
|
79.4 ± 7.4*#$
|
48.2 ± 2.7
|
- RMP resting membrane potential; V
max
maximum rate of depolarization of action potential (AP). Data are means ± SEM, n is the number of cells studied. *P < 0.05 vs. 0 day of differentiation (day 0, undifferentiated cells); #P < 0.05 vs. cells after 9 days of differentiation (day 9); $P < 0.05 vs. cells after 21 days of differentiation (day 21) without AP.
