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Table 2 Top 10 enriched functional GO clusters in neuronal PC12-specific GR binding regions (GBS)

From: A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells

  Neuronal PC212 unique GBS
GO Term Category Enrichment score
1 neuron development BP 4.4
2 cytoplasmic vesicle CC 3.4
3 neuron projection CC 3.1
4 metal ion binding MF 3.0
5 blood vessel development BP 3.0
6 cell motion BP 2.8
7 identical protein binding MF 2.6
8 biogenic amine biosynthetic process BP 2.6
9 synapse CC 2.2
10 protein tyrosine kinase activity MF 2.0
  1. Gene ontology analysis of genes associated with GBS identified in neuronal PC12 cells. The 10 most enriched functional GO clusters in GBS that are uniquely found in neuronal PC12 cells. Analysis was performed with the Database for Annotation, Visualization and Integrated Discovery (DAVID). Per cluster, the first GO-term is shown. In addition, the category to which the GO term belongs to is indicated, i.e. Biological Processes (BP), Molecular Function (MF) or Cellular Compartment (CC). The enrichment score indicates the geometric mean (in -log scale) of p-value of the GO cluster.
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